Evaluation of the Effect of the Intensity and Occurrence of Postoperative Pain of Resin-Based and Bioceramic Root Canal Sealers: A Systematic Review and Meta-Analysis of Randomized Controlled Trial Studies

Objective:  To evaluate resin- and bioceramic root canal sealers affect postoperative intensity pain occurrence .  Material Methods:  From the electronic databases, PubMed, Cochrane Library, Embase, ISI have been used to perform systematic literature until September 2020. Electronic titles were managed using Endnote X8 software. They performed searches with mesh terms. Two reviewers blindly independently extracted data from studies that included for extraction.  Results: A total of 186 potentially relevant abstracts found. Finally, four included. Pain score was (RR = -0.20; 95% CI -1.09–0.68; p= 0.65). This result showed no statistically significant difference resin-based after 24 hours between VAS scores Conclusion:  Postoperative low in Patients requiring retreatment obturated or bioceramic-based without extrusion beyond apex. No differences observed 48 postoperatively.